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Index > Protein center > Havcr1(Gene name) > Mouse
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  • Havcr1 (Gene name),
  • Hepatitis A virus cellular receptor 1 homolog (Protein name ),  HAVR1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Havcr1(Kim1;Tim1;Timd1);
    Protein name:
    Hepatitis A virus cellular receptor 1 homolog(HAVcr-1);
    Alternative:
    T cell immunoglobulin and mucin domain-containing protein 1(TIMD-1);Kidney injury molecule 1(KIM-1);TIM-1(TIM-1);T cell membrane protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    305
    Sequence:
    50:
    MNQIQVFISG | LILLLPGAVD | SYVEVKGVVG | HPVTLPCTYS | TYRGITTTCW | 
    100:
    GRGQCPSSAC | QNTLIWTNGH | RVTYQKSSRY | NLKGHISEGD | VSLTIENSVE | 
    150:
    SDSGLYCCRV | EIPGWFNDQK | VTFSLQVKPE | IPTRPPTRPT | TTRPTATGRP | 
    200:
    TTISTRSTHV | PTSIRVSTST | PPTSTHTWTH | KPEPTTFCPH | ETTAEVTGIP | 
    250:
    SHTPTDWNGT | VTSSGDTWSN | HTEAIPPGKP | QKNPTKGFYV | GICIAALLLL | 
    300:
    LLVSTVAITR | YILMKRKSAS | LSVVAFRVSK | IEALQNAAVV | HSRAEDNIYI | 
    305:
    VEDRP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse HAVcr-1
    Cat.:
    E0785m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse HAVcr-1
    Cat.:
    E0785h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse HAVcr-1
    Cat.:
    E0785r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse HAVcr-1
    Cat.:
    U0785h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse HAVcr-1
    Cat.:
    U0785m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse HAVcr-1
    Cat.:
    U0785r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse HAVcr-1
    Cat.:
    P0785Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse HAVcr-1
    Cat.:
    P0785Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse HAVcr-1
    Cat.:
    P0785Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse HAVcr-1
    Monoclonal Antibody for Mouse HAVcr-1
    Monoclonal Antibody for Mouse HAVcr-1
    Protein for Mouse HAVcr-1
    Protein for Mouse HAVcr-1
    Protein for Mouse HAVcr-1
    Cat.:
    R0785m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤3.6%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤6.9%

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.8%

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.5%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤8.9%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery

    Recovery was determined by spiking various levels of HAVcr-1 into serum and plasma .

    Sample Type

    Average(%)

    Recovery  Range (%)

    Serum

    95

    92-98

    Plasma

    89

    86-93

    Recovery was determined by spiking various levels of HAVcr-1 into serum and plasma .

    Sample Type

    Average(%)

    Recovery  Range (%)

    Serum

    104

    94-110

    Plasma

    96

    89-105

     

     

     

     

    Recovery was determined by spiking various levels of HAVcr-1 into serum and plasma .

    Sample Type

    Average(%)

    Recovery  Range (%)

    Serum

    102

    95-114

    Plasma

    96

    93-99

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of HAVcr-1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    89-93%

    89-101%

    86-99%

    93-102%

    EDTA plasma(n=5)

    92-104%

    88-101%

    82-93%

    86-91%

    heparin plasma(n=5)

    86-98%

     

    84-95%

    83-92%

    90-103%

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of HAVcr-1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample               

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    89-103%

    86-101%

    83-99%

    97-110%

    EDTA plasma(n=5)

    97-108%

    88-101%

    79-102%

    89-99%

    heparin plasma(n=5)

    86-98%

     

    86-99%

    94-108%

    90-103%

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of HAVcr-1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    89-101%

    90-105%

    93-97%

    93-107%

    EDTA plasma(n=5)

    95-110%

    89-97%

    94-110%

    88-99%

    heparin plasma(n=5)

    86-99%

     

    88-96%

    99-114%

    92-105%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family."
      McIntire J.J. , Umetsu S.E. , Akbari O. , Potter M. , Kuchroo V.K. , Barsh G.S. , Freeman G.J. , Umetsu D.T. , DeKruyff R.H.
      Nat. Immunol.2:1109-1116(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);VARIANTS HBA;TISSUE SPECIFICITY
      strain: BALB/c.
      tissue: Spleen.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Blastocyst.
    4. 4.
      "TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation."
      Meyers J.H. , Chakravarti S. , Schlesinger D. , Illes Z. , Waldner H. , Umetsu S.E. , Kenny J. , Zheng X.X. , Umetsu D.T. , DeKruyff R.H. , Strom T.B. , Kuchroo V.K.
      Nat. Immunol.6:455-464(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A RECEPTOR FOR TIMD4
    5. 5.
      "Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family."
      Santiago C. , Ballesteros A. , Tami C. , Martinez-Munoz L. , Kaplan G.G. , Casasnovas J.M.
      Immunity26:299-310(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 20-130
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